Jacques Banchereau, Ph.D., is the Director of Baylor Institute for Immunology Research (BIIR) in Dallas. He received his Ph.D. in Biochemistry from the University of Paris and later served as director of the Schering Plough Laboratory for Immunological Research, where he was among the first to discover how to grow human dendritic cells. At Schering Plough he led work on the biology of B lymphocytes and novel human cytokines, including IL-4, IL-5, IL-10, IL-13 and IL-17.
Today he leads a team of nearly eighty researchers in projects on autoimmune diseases, cancer, infectious diseases and responses to biothreats. At the heart of Dr. Banchereau’s research interests is the ability to quickly move clinically-relevant laboratory findings from ‘bench-to-bedside’ by teaming researchers with clinicians.
BIIR researchers seek to understand and exploit dendritic cells, the primary antigen presentation cells of the immune system. Dendritic cell based vaccines against metastatic melanoma have yielded significant immunological and clinical responses in a series of Phase I and II clinical trials.
Dr. Banchereau’s group has developed a new treatment for juvenile arthritis patients who do not respond to conventional therapies. They have also identified key immune system alterations in patients suffering from lupus.
Dr. Banchereau is the Principal Investigator on a multi-institutional Human Immunology and Biodefense grant. Dr. Banchereau holds Adjunct Professorships at Baylor University in Waco, TX and the University of Texas Southwestern Medical Center in Dallas. He has published over 250 journal articles as well as 150 book chapters and reviews.